Intern
    Institut für Anatomie und Zellbiologie

    Publikationen 2024

    Götz L, Rueckschloss U, Reimer A, Bömmel H, Beilhack A, Ergün S, Kleefeldt F.
    Vascular inflammaging: Endothelial CEACAM1 expression is upregulated by TNF-α via independent activation of NF-κB and β-catenin signaling.
    Aging Cell. 2024 Oct 21:e14384. doi: 10.1111/acel.14384. Epub ahead of print. PMID: 39434463.

    Gurski, F., Shirvanchi, K., Rajendran, V., Rajendran, R., Megalofonou, F.-F., Böttiger, G., Stadelmann, C., Bhushan, S., Ergün, S., Karnati, S., & Berghoff, M. (2024).
    Anti-inflammatory and remyelinating effects of fexagratinib in experimental multiple sclerosis.
    British Journal of Pharmacology, 120. https://doi.org/10.1111/bph.17341

    Pratama AM, Sharma M, Naidu S, Bömmel H, Prabhuswamimath SC, Thati M, Wihadmadyatami H, Bachhuka A, Karnati S. Peroxisomes and PPARs:
    Emerging role as master regulators of cancer metabolism.
    Mol Metab. 2024 Oct 3:102044. doi: 10.1016/j.molmet.2024.102044. Epub ahead of print. PMID: 39368612.

    Boateng E, Bonilla-Martinez R, Ahlemeyer B, Garikapati V, Alam MR, Trompak O, Oruqaj G, El-Merhie N, Seimetz M, Ruppert C, Günther A, Spengler B, Karnati S, Baumgart-Vogt E.
    It takes two peroxisome proliferator-activated receptors (PPAR-β/δ and PPAR-γ) to tango idiopathic pulmonary fibrosis.
    Respir Res. 2024 Sep 23;25(1):345. doi: 10.1186/s12931-024-02935-7. PMID: 39313791.

    Hoffmann H, Wartenberg M, Vorlova S, Karl-Schöller F, Kallius M, Reinhardt O, Öztürk A, Schuhmair LS, Burkhardt V, Gätzner S, Scheld D, Nandigama R, Zernecke A, Herterich S, Ergün S, Rosenwald A, Henke E. Normalization of Snai1-mediated vessel dysfunction increases drug response in cancer.
    Oncogene. 2024 Aug;43(35):2661-2676. doi: 10.1038/s41388-024-03113-1. Epub 2024 Aug 2. PMID: 39095583; PMCID: PMC11347376.

    Hartung V, Hendel R, Huflage H, Augustin AM, Grunz JP, Kleefeldt F, Peter D, Lichthardt S, Ergün S, Bley TA, Gruschwitz P.
    Ultra-high Versus Standard Resolution Photon-Counting Detector CT Angiography for Imaging of Femoral Stents in a Cadaveric Perfusion Model.
    Acad Radiol. 2024 Aug 6:S1076-6332(24)00474-4. doi: 10.1016/j.acra.2024.07.038. Epub ahead of print. PMID: 39112296.

    Kundu I, Varshney S, Karnati S, Naidu S.
    The multifaceted roles of circular RNAs in cancer hallmarks: From mechanisms to clinical implications.
    Mol Ther Nucleic Acids. 2024 Jul 20;35(3):102286. doi: 10.1016/j.omtn.2024.102286. PMID: 39188305; PMCID: PMC11345389.

    Naidu S, Karnati S, Radhakrishnan H, Gupta A. Editorial:
    Role of non-coding RNAs (emphasis on the emerging role of circular RNAs) in cancer. Application potential for molecular diagnostics and therapeutics of cancer.Front Genet. 2024 Jul 25;15:1450309. doi: 10.3389/fgene.2024.1450309. PMID: 39119580; PMCID: PMC11306118.

    Hachmann Malte , Gülcan Güntas , Rajendran Ranjithkumar , Höring Marcus , Liebisch Gerhard , Bachhuka Akash , Kohlhaas Michael , Maack Christoph , Ergün Süleyman , Dudek Jan , Karnati SrikanthTafazzin deficiency causes substantial remodeling in the lipidome of a mouse model of Barth Syndrome cardiomyopathy
    Frontiers in Molecular Medicine. 2024. doi: 10.3389/fmmed.2024.1389456

    Grunz JP, Kunz AS, Paul MM, Luetkens KS, Huflage H, Conrads N, Ergün S, Weber T, Herbst M, Herold S, Bley TA, Patzer TS.
    Postoperative Extremity Tomosynthesis-A Superimposition-Free Alternative to Standard Radiography?
    Invest Radiol. 2024 May 7. doi: 10.1097/RLI.0000000000001085. Epub ahead of print. PMID: 38709665.

    Conrads N, Kunz AS, Huflage H, Patzer TS, Luetkens KS, Ergün S, Herbst M, Herold S, Weber T, Bley TA, Grunz JP.
    Upright Tomosynthesis of the Lumbar Spine.
    Acad Radiol. 2024 Apr;31(4):1472-1479. doi: 10.1016/j.acra.2023.08.036. Epub 2023 Sep 18. PMID: 37730493.

    Yuki K, Vallon M, Ding J, Rada CC, Tang AT, Vilches-Moure JG, McCormick AK, Echeverri MFH, Alwahabi S, Braunger BM, Ergün S, Kahn ML, Kuo CJ.
    GPR124 regulates murine brain embryonic angiogenesis and BBB formation by an intracellular domain-independent mechanism.
    Development. 2024 Apr 29:dev.202794. doi: 10.1242/dev.202794. Epub ahead of print. PMID: 38682276.

    Ascheid D, Baumann M, Pinnecker J, Friedrich M, Szi-Marton D, Medved C, Bundalo M, Ortmann V, Öztürk A, Nandigama R, Hemmen K, Ergün S, Zernecke A, Hirth M, Heinze KG, Henke E.
    A vascularized breast cancer spheroid platform for the ranked evaluation of tumor microenvironment-targeted drugs by light sheet fluorescence microscopy.
    Nat Commun. 2024 Apr 27;15(1):3599. doi: 10.1038/s41467-024-48010-z. PMID: 38678014; PMCID: PMC11055956.

    Feldle P, Grunz JP, Huflage H, Kunz AS, Ergün S, Afat S, Gruschwitz P, Görtz L, Pennig L, Bley TA, Conrads N.
    Influence of helical pitch and gantry rotation time on image quality and file size in ultrahigh-resolution photon-counting detector CT.
    Sci Rep. 2024 Apr 23;14(1):9358. doi: 10.1038/s41598-024-59729-6. PMID: 38653758; PMCID: PMC11039754.

    Hartung V, Gruschwitz P, Huflage H, Augustin AM, Kleefeldt F, Peter D, Lichthardt S, Ergün S, Bley TA, Grunz JP, Petritsch B.
    Photon-Counting Detector CT for Femoral Stent Imaging in an Extracorporeally Perfused Human Cadaveric Model.
    Invest Radiol. 2024 Apr 1;59(4):320-327. doi: 10.1097/RLI.0000000000001019. Epub 2023 Oct 7. PMID: 37812470.

    Huflage H, Hendel R, Kunz AS, Ergün S, Afat S, Petri N, Hartung V, Gruschwitz P, Bley TA, Grunz JP.
    Investigating the Small Pixel Effect in Ultra-High Resolution Photon-Counting CT of the Lung.
    Invest Radiol. 2024 Apr 1;59(4):293-297. doi: 10.1097/RLI.0000000000001013. PMID: 37552040.

    Patzer TS, Kunz AS, Huflage H, Conrads N, Luetkens KS, Pannenbecker P, Ergün S, Herbst M, Herold S, Weber T, Bley TA, Grunz JP.
    Tomosynthesis of the Appendicular Skeleton on a Twin Robotic X-ray System: A Cadaveric Fracture Study.
    Acad Radiol. 2024 Mar 5:S1076-6332(24)00090-4. doi: 10.1016/j.acra.2024.02.020. Epub ahead of print. PMID: 38448327.

    Hartung V, Augustin AM, Grunz JP, Huflage H, Hennes JL, Kleefeldt F, Ergün S, Peter D, Lichthardt S, Bley TA, Gruschwitz P.Training for endovascular therapy of acute arterial disease and procedure-related complication: An extracorporeally-perfused human cadaver model study.
    PLoS One. 2024 Feb 8;19(2):e0297800. doi: 10.1371/journal.pone.0297800. PMID: 38330071; PMCID: PMC10852297.

    Janz A, Walz K, Cirnu A, Surjanto J, Urlaub D, Leskien M, Kohlhaas M, Nickel A, Brand T, Nose N, Wörsdörfer P, Wagner N, Higuchi T, Maack C, Dudek J, Lorenz K, Klopocki E, Ergün S, Duff HJ, Gerull B.
    Mutations in DNAJC19 cause altered mitochondrial structure and increased mitochondrial respiration in human iPSC-derived cardiomyocytes.
    Mol Metab. 2024 Jan;79:101859. doi: 10.1016/j.molmet.2023.101859. Epub 2023 Dec 23. PMID: 38142971; PMCID: PMC10792641.

    Rani A, Ergün S, Karnati S, Jha HC.
    Understanding the link between neurotropic viruses, BBB permeability, and MS pathogenesis.
    J Neurovirol. 2024 Jan 8. doi: 10.1007/s13365-023-01190-8. Epub ahead of print. PMID: 38189894.

    Huflage H, Hendel R, Woznicki P, Conrads N, Feldle P, Patzer TS, Ergün S, Bley TA, Kunz AS, Grunz JP.
    The Small Pixel Effect in Ultra-High-Resolution Photon-Counting CT of the Lumbar Spine.
    Invest Radiol. 2024 Feb 8. doi: 10.1097/RLI.0000000000001069. Epub ahead of print. PMID: 38329822.

    Feldle P, Grunz JP, Kunz AS, Pannenbecker P, Patzer TS, Pichlmeier S, Sauer ST, Hendel R, Ergün S, Bley TA, Huflage H.
    Influence of spectral shaping and tube voltage modulation in ultralow-dose computed tomography of the abdomen.
    BMC Med Imaging. 2024 Feb 23;24(1):49. doi: 10.1186/s12880-024-01228-1. PMID: 38395772; PMCID: PMC10893640.