Publikationen 2018
Nandigama R, Upcin B, Aktas BH, Ergün S, Henke E.
Restricion of drug transport by the tumor environment
Histochem Cell Biol. 2018 Dec 25. doi: 10.1007/s00418-018-1744-z
Engevik AC, Kaji I, Engevik MA, Meyer AR, Weis VG, Goldstein A, Hess MW, Müller T, Koepsell H, Dudeja PK, Tyska M, Huber LA, Shub MD, Ameen N, Goldenring JR
Loss of MYO5B Leads to Reductions in Na+ Absorption With Maintenance of CFTR-Dependent Cl- Secretion in Enterocytes
Gastroenterology. 2018 Dec;155(6):1883-1897.e10. doi: 10.1053/j.gastro.2018.08.025. Epub 2018 Aug 23.
Klein T, Henkel L, Klug K, Kwok CK, Klopocki E, Üçeyler N.
Generation of the human induced pluripotent stem cell line UKWNLi002-A from dermal fibroblasts of a woman with a heterozygous c.608 C>T (p.Thr203Met) mutation in exon 3 of the nerve growth factor gene potentially associated with hereditary sensory and autonomic neuropathy type 5.
Stem Cell Res. 2018 Dec; 12;33:171-174. doi: 10.1016/j.scr.2018.10.017
Nose N, Werner RA, Ueda Y, Günther K, Lapa C, Javadi MS, Fukushima K, Edenhofer F, Higuchi T.
Metabolic substrate shift in human induced pluripotent stem cells during cardiac differentiation: Functional assessment using in vitro radionuclide uptake assay.
Int J Cardiol. 2018 Oct 15;269:229-234. doi: 10.1016/j.ijcard.2018.06.089
Schäfer N1, Friedrich M2, Jørgensen ME1, Kollert S2,3,4, Koepsell H1, Wischmeyer E3,5, Lesch KP2,4,6, Geiger D1, Döring F
Functional analysis of a triplet deletion in the gene encoding the sodium glucose transporter 3, a potential risk factor for ADHD
PLoS One. 2018 Oct 4;13(10):e0205109. doi: 10.1371/journal.pone.0205109. eCollection 2018.
Masuda T, Watanabe Y, Fukuda K, Watanabe M, Onishi A, Ohara K, Imai T, Koepsell H, Muto S, Vallon V, Nagata D
Unmasking a sustained negative effect of SGLT2 inhibition on body fluid volume in the rat
Am J Physiol Renal Physiol. 2018 Sep 1;315(3):F653-F664. doi: 10.1152/ajprenal.00143.2018. Epub 2018 May 23
Matsushita N, Ishida N, Ibi M, Saito M, Sanbe A, Shimojo H, Suzuki S, Koepsell H, Takeishi Y, Morino Y, Taira E, Sawa Y, Hirose M
Chronic Pressure Overload Induces Cardiac Hypertrophy and Fibrosis via Increases in SGLT1 and IL-18 Gene Expression in Mice
Int Heart J. 2018 Sep 26;59(5):1123-1133. doi: 10.1536/ihj.17-565. Epub 2018 Aug 11.
PPARα-mediated Peroxisome Induction Compensates PPARγ-deficiency in Bronchiolar Club Cells
PLoS One 2018 Sep 13;13(9):e0203466. doi: 10.1371/journal.pone.0203466. eCollection 2018.
Mekala SR, Wörsdörfer P, Bauer J, Stoll O, Wagner N, Reeh L, Loew K, Eckner G, Kwok CK,
Wischmeyer E, Dickinson ME, Schulze H, Stegner D, Benndorf RA, Edenhofer F, Pfeiffer V, Kuerten S, Frantz S, Ergün S.
Generation of Cardiomyocytes From Vascular Adventitia-Resident Stem Cells
Circ Res. 2018 Aug 31;123(6):686-699. doi: 10.1161/CIRCRESAHA.117.312526
Fu Y, Breljak D, Onishi A, Batz F, Patel R, Huang W, Song P, Freeman B, Mayoux E, Koepsell H, Anzai N, Nigam SK, Sabolic I, Vallon V
Organic anion transporter OAT3 enhances the glucosuric effect of the SGLT2 inhibitor empagliflozin
Am J Physiol Renal Physiol. 2018 Aug 1;315(2):F386-F394. doi: 10.1152/ajprenal.00503.2017. Epub 2018 Feb 7.
Werner RA, Wakabayashi H, Bauer J, Schütz C, Zechmeister C, Hayakawa N, Javadi MS, Lapa C, Jahns R, Ergün S, Jahns V, Higuchi T.
Longitudinal 18F-FDG PET imaging in a rat model of autoimmune myocarditis
Eur Heart J Cardiovasc Imaging. 2018 Aug 8. doi: 10.1093/ehjci/jey119
Simon M, Ipek R, Homola GA, Rovituso DM, Schampel A, Kleinschnitz C, Kuerten S.Anti-CD52 antibody treatment depletes B cell aggregates in the central nervous system in a mouse model of multiple sclerosis
J Neuroinflammation. 2018 Aug 11;15(1):225. doi: 10.1186/s12974-018-1263-9
Klein T, Günther K, Kwok CK, Edenhofer F, Üçeyler N.
Generation of the human induced pluripotent stem cell line (UKWNLi001-A) from skin fibroblasts of a woman with Fabry disease carrying the X-chromosomal heterozygous c.708 G > C (W236C) missense mutation in exon 5 of the alpha-galactosidase-A gene.
Stem Cell Res. 2018 Aug;31:222-226. doi: 10.1016
Chintalapati C, Keller T, Mueller TD, Gorboulev V, Schäfer N, Zilkowski I, Veyhl-Wichmann M, Geiger D, Groll J, Koepsell H.
RS1 (RSC1A1) Downregulates the Exocytotic Pathway of Glucose Transporter SGLT1 at Low Intracellular Glucose via Inhibition of Ornithine Decarboxylase
J Neurochem. 2018 Jul 19. doi: 10.1111/jnc.14551
Mühlemann M, Zdzieblo D, Friedrich A, Berger C, Otto C, Walles H, Koepsell H, Metzger M
Altered pancreatic islet morphology and function in SGLT1 knockout mice on a glucose-deficient, fat-enriched diet
Mol Metab. 2018 Jul;13:67-76. doi: 10.1016/j.molmet.2018.05.011. Epub 2018 May 23.
Pfeiffer V, Götz R, Camarero G, Heinsen H, Blum R, Rapp UR. (2018)
Impaired neuronal maturation of hippocampal neural progenitor cells in mice lacking CRAF
PLoS ONE 13(3): e0192067
Wörsdörfer P, Wagner N, Ergün S. (2018)
The role of connexins during early embryonic development: pluripotent stem cells, gene editing, and artificial embryonic tissues as tools to close the knowledge gap
Histochem Cell Biol. 2018 Jul 23. doi: 10.1007/s00418-018-1697-2
Rossow L, Veitl S, Vorlová S, Wax JK, Kuhn AE, Maltzahn V, Upcin B, Karl F, Hoffmann H, Gätzner S, Kallius M, Nandigama R, Scheld D, Irmak S, Herterich S, Zernecke A, Ergün S, Henke E. (2018)
LOX-catalyzed collagen stabilization is a proximal cause for intrinsic resistance to chemotherapy
Oncogene. 2018 May 21. doi: 10.1038/s41388-018-0320-2.
Ghavampour S, Kleefeldt F, Bömmel H, Volland J, Paus A, Horst A, Pfeiffer V, Hübner S, Wagner N, Rueckschloss U, Ergün S. (2018)
Endothelial barrier function is differentially regulated by CEACAM1-mediated signaling
FASEB J.2018 May 10:fj201800331R. doi: 10.1096/fj.201800331R
Pastak M, Kleff V, Saban DR, Czugala M, Steuhl KP, Ergün S, Singer BB, Fuchsluger TA. (2018)
Gene Therapy for Modulation of T-Cell-Mediated Immune Response Provoked by Corneal Transplantation
Hum Gene Ther. 2018 Apr;29(4):467-479. doi: 10.1089/hum.2017.044.
Gorboulev V, Rehman S, Albert CM, Roth U, Meyer MJ, Tzvetkov MV, Mueller TD, Koepsell H.
Assay Conditions Influence Affinities of Rat Organic Cation Transporter 1: Analysis of Mutagenesis in the Modeled Outward-Facing Cleft by Measuring Effects of Substrates and Inhibitors on Initial Uptake
Mol Pharmacol. 2018 Apr;93(4):402-415. doi: 10.1124/mol.117.11076
Jansch C, Günther K, Waider J, Ziegler GC, Forero A, Kollert S, Svirin E, Pühringer D, Kwok CK, Ullmann R, Maierhofer A, Flunkert J, Haaf T, Edenhofer F, Lesch KP. (2018)
Generation of a human induced pluripotent stem cell (iPSC) line from a 51-year-old femal with attention-deficit/hyperactivity disorder (ADHA) carrying a duplication of SLC2A3
Stem Cell Res. 2018 Apr;28:136-140. doi: 10.1016/j.scr.2018.02.005
Peruzzotti-Jametti L, Bernstock JD, Vicario N, Costa ASH, Kwok CK, Leonardi T, Booty LM, Bicci I, Balzarotti B, Volpe G, Mallucci G, Manferrari G, Donegà M, Iraci N, Braga A, Hallenbeck JM, Murphy MP, Edenhofer F, Frezza C, Pluchino S.
Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation
Cell Stem Cell. 2018 Mar 1;22(3):355-368.e13. doi: 10.1016/j.stem.2018.01.020.
Kwok CK, Ueda Y, Kadari A, Günther K, Ergün S, Heron A, Schnitzler AC, Rook M, Edenhofer F. (2018)Scalable stirred suspension culture for the generation of billions of human induced pluripotent stem cells using single-use bioreactors
J Tissue Eng Regen Med. 2018 Feb;12(2):e1076-e1087. doi: 10.1002/term.2435.
Wörsdörfer P, Ergün S.
Do Vascular Mural Cells Possess Endogenous Plasticity In Vivo?
Stem Cell Rev. 2018 Feb;14(1):144-147. doi: 10.1007/s12015-017-9791-8
